851077-19-5Relevant articles and documents
Microwave-assisted synthesis of phenylpyrimidine derivatives via Suzuki-Miyaura reactions in water
Le, Yi,Zhang, Yan,Wang, Qin,Rao, Nian,Li, Dan,Liu, Li,Ouyang, Guiping,Yan, Longjia
, (2021)
An efficient method was developed to prepare biphenylpyrimidine scaffolds via a Suzuki-Miyaura coupling reaction. In this procedure, the products were synthesized under microwave irradiation in water and analogues of biguanidine were employed as ligands.
Phenyl derivatives, their manufacture and use as pharmaceutical agents
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Page/Page column 54, (2010/02/11)
This invention relates to compounds of the formula wherein one of R5, R6 and R7 is and X1, X2, Y1 to Y4, R1 to R13 and m and n are defined in the description, and to all enantiomers and pharmaceutically acceptable salts and/or esters thereof. The invention further relates to pharmaceutical compositions containing such compounds, to a process for their preparation and to their use for the treatment and/or prevention of diseases which are modulated by PPARδ and/or PPARα agonists.