85121-45-5

Basic information

• Product Name: methyl cis-3-hydroxy-2,2-dimethyl-6-methylenecyclohexanecarboxylate
• CAS NO: 85121-45-5
• Molecular Weight: 198.262
• Mol File: 85121-45-5.mol

Chemical Properties

• CAS DataBase Reference: methyl cis-3-hydroxy-2,2-dimethyl-6-methylenecyclohexanecarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl cis-3-hydroxy-2,2-dimethyl-6-methylenecyclohexanecarboxylate(85121-45-5)
• EPA Substance Registry System: methyl cis-3-hydroxy-2,2-dimethyl-6-methylenecyclohexanecarboxylate(85121-45-5)

Safety Data

• Hazardous Substances Data: 85121-45-5(Hazardous Substances Data)

Upstream product

• 81752-85-4 methyl (Z)-7-methyl-3-((trimethylsilyl)methyl)octa-2,6-dienoate 
• 103142-50-3 methyl(Z)-6,7-epoxy-7-methyl-3-<(trimethylsilyl)methyl>-2-octenoate 

Downstream Products

• 19901-96-3 (+/-)-Karahana ether 
• 72445-03-5 (1RS,3SR)-3-(hydroxymethyl)-2,2-dimethyl-4-methylenecyclohexanol 

Relevant articles and documents

Synthesis of (+/-)-karahana ether and a (+/-)-labdadienoic acid by the electrophilic cyclization of epoxy allylsilanes

The epoxy allylsilanes 7 and 16 were synthesized by stereoselective routes from β-keto esters and cyclized with Lewis acids in good yield.The monocyclic product from 7 was converted into (+/-)-karahana ether (10), and the bicyclic product from 20 was used in a synthesis of the 3-hydroxylabdadienoic acid 24b.

Stereoselective cyclization of epoxy allylsilanes. A synthesis of karahana ether

Epoxy allylsilanes can be cyclized with Lewis acids to give cyclic alcohols in a biomimetic synthesis of mono and bicyclic compounds.The allylsilane has a pronounced effect on activating an olefin in this cyclization and producing the exocyclic methylene