851230-05-2Relevant academic research and scientific papers
Methyl scanning: Total synthesis of demethylasterriquinone B1 and derivatives for identification of sites of interaction with and isolation of its receptor(s)
Pirrung, Michael C.,Liu, Yufa,Deng, Liu,Halstead, Diana K.,Li, Zhitao,May, John F.,Wedel, Michael,Austin, Darrell A.,Webster, Nicholas J. G.
, p. 4609 - 4624 (2007/10/03)
The principle of methyl scanning is proposed for determination of the sites of interaction between biologically active small molecules and their macromolecular target(s). It involves the systematic preparation of a family of methylated derivatives of a co
