851231-25-9

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 80-46-6 4-t-amylphenol 

Downstream Products

• 851199-04-7 2-[4-(1,1-dimethylpropyl)phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 57263-21-5 4-tert-pentyl-bromobenzene 

Relevant academic research and scientific papers

MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS

Provided herein are antibacterial compounds, wherein the compounds in some embodiments have broad spectrum bioactivity. In various embodiments, the compounds act by inhibition of bacterial type 1 signal peptidases SpsB and/or LepB, an essential protein in bacteria. Pharmaceutical compositions and methods for treatment using the compounds described herein are also provided.

IRIDIUM COMPLEX MIXTURE, ORGANIC ELECTROLUMINESCENT ELEMENT AND METHOD FOR PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide: an iridium complex mixture that is excellent in solubility, can be easily produced, and is excellent in durability of an element; an organic electroluminescent element using the iridium complex mixture; and a method for producing the same. SOLUTION: The iridium complex mixture has two or more iridium complexes represented by general formula (1) defined by (A)mIr(B)n [A and B are bidentate ligands having different structures; A has a structure represented by general formula (2), where R1 to R3 are alkyl groups; and m is an integer from 0 to 2, and n is an integer from 1 to 3, satisfying m+n=3]. The bidentate ligands represented by B in the formula of at least two iridium complexes among the two or more iridium complexes are bidentate ligands having the same structure. COPYRIGHT: (C)2016,JPO&INPIT

Organoiridium complex mixture, and its manufacturing method and an organic electroluminescence element (by machine translation)

PROBLEM TO BE SOLVED: To provide an iridium complex mixture that is excellent in solubility in solvents, is high in yield, can easily be produced, and is excellent in the durability of an element, when used for an organic electroluminescent element, to provide an organic electroluminescent element using the iridium complex mixture, and to provide a method for producing the same. SOLUTION: The iridium complex mixture having two or more iridium complexes represented by following general formula (1), wherein bidentate ligands represented by B in the formula (1), of at least two iridium complexes among the two or more iridium complexes are bidentate ligands having the same structure. In (A)mIr(B)n(1), A and B are bidentate ligands having different structures, respectively; A has a structure represented by general formula (2), (wherein, R1, R2and R3are each independently, alkyl); m is an integer of 0 to 2; n is an integer of 1 to 3; m+n=3. COPYRIGHT: (C)2012,JPO&INPIT

The conversion of phenols to the corresponding aryl halides under mild conditions

Mild, novel procedures have been developed for the syntheses of aryl halides from the corresponding phenols in modest to good yields via boronate ester intermediates.

PYRROLE AND PYRAZOLE DERIVATIVES AS POTENTIATORS OF GLUTAMATE RECEPTORS

The present invention relates to pyrrole and pyrazole compounds of formula (I) and their pharmaceutically acceptable salts, and further relates to their use in treating schizophrenia, cognitive deficits associated with schizophrenia, Alzheimer's disease, dementia of the Alzheimer's type, mild cognitive impairment, or depression. The compounds act as potentiators on glutamate receptors, in particular AMPA and the GluR family.