85125-39-9Relevant academic research and scientific papers
N-Alkylation of amines through hydrogen borrowing over a heterogeneous Cu catalyst
Santoro, Federica,Psaro, Rinaldo,Ravasio, Nicoletta,Zaccheria, Federica
, p. 2596 - 2600 (2014)
Substitution of alkylhalides for the synthesis of amines is a relevant target for synthetic chemists. Secondary amines can be obtained in a one pot-one step reaction from secondary and benzylic alcohols and aniline over a heterogeneous copper catalyst. The process does not require any additive, is intrinsically safe and produces no waste.
Ni-Cu/γ-Al2O3 catalyzed N-alkylation of amines with alcohols
Sun, Jian,Jin, Xiaodong,Zhang, Fengwei,Hu, Wuquan,Liu, Juntao,Li, Rong
experimental part, p. 30 - 33 (2012/07/17)
A γ-Al2O3 supported Ni and Cu bimetallic nanoparticles catalyst (45 wt.% Ni, Ni/Cu mass ratio = 4.5/1.0) is prepared by electroless plating method for the N-alkylation of amines with alcohols under base and Lewis acidic cocatalyst conditions. The catalyst afforded fast conversions, high selectivity for amines and alcohols with various structures under an Ar atmosphere in o-xylene. Furthermore, catalyst still has a stable catalytic activity after two consecutive cycles regenerated.
