851303-95-2Relevant academic research and scientific papers
Toll-like receptor 2 antagonists. Part 1: Preliminary SAR investigation of novel synthetic phospholipids
Spyvee, Mark R.,Zhang, Huiming,Hawkins, Lynn D.,Chow, Jesse C.
, p. 5494 - 5498 (2008/09/21)
Novel synthetic phospholipid compound 1 was discovered to be an antagonist of human toll-like receptor 2 (TLR2) signaling. In a preliminary SAR campaign we synthesized several analogues of 1 and found that considerable structural changes could be made wit
COMPOUNDS AND METHODS FOR TREATING TOLL-LIKE RECEPTOR 2-RELATED DISEASES AND CONDITIONS
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Page/Page column 90, (2008/06/13)
The present invention relates to compounds and methods useful in the prevention or treatment of diseases or conditions associated with Toll-like receptor 2 activation.
