851306-99-5Relevant articles and documents
INHIBITORS OF DIPEPTIDYL PEPTIDASE IV
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Page/Page column 46-47, (2010/02/11)
The invention relates to compounds of the formula (I) or pharmaceutically-acceptable salts thereof wherein Ar, R 1 , R2 , R 3 , R 4 , R 5 , R 6 , R 7 and R 8 have any of the meanings defined in the description, which possess dipeptidyl peptidase IV (DPP-IV) inhibitory activity and accordingly have value in the treatment of disease states associated with DPP-IV activity, such as diabetes mellitus. Processes for the preparation of said compounds, intermediates in said processes, pharmaceutical compositions containing said compounds or salts, and the use of said compounds or salts are also described.