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Methanone, 3,9-diazaspiro[5.5]undec-3-ylphenyl-, also known as Umeclidinium, is a chemical compound that functions as a long-acting muscarinic antagonist (LAMA). It is utilized in the management of chronic obstructive pulmonary disease (COPD) and asthma, working by inhibiting the muscarinic receptors in the airways, which results in smooth muscle relaxation and bronchodilation, thereby enhancing airflow to the lungs.
Used in Pharmaceutical Industry:
Methanone, 3,9-diazaspiro[5.5]undec-3-ylphenylis used as a therapeutic agent for the treatment of chronic obstructive pulmonary disease (COPD) and asthma. It is employed for its ability to block the action of acetylcholine at the muscarinic receptors, leading to improved lung function and reduced exacerbations in affected patients.
Used in Respiratory Treatment:
Methanone, 3,9-diazaspiro[5.5]undec-3-ylphenylis used as a bronchodilator to facilitate smooth muscle relaxation in the airways. This application aids in the treatment of respiratory conditions by improving airflow to the lungs, thus providing relief from symptoms associated with COPD and asthma.
Used in Combination Therapy:
Methanone, 3,9-diazaspiro[5.5]undec-3-ylphenylis used in combination with long-acting beta agonists as part of a comprehensive treatment approach for respiratory conditions. This combined use aims to enhance the overall effectiveness of treatment and manage symptoms more effectively than single-agent therapies.

851322-39-9

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851322-39-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 851322-39-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,3,2 and 2 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 851322-39:
(8*8)+(7*5)+(6*1)+(5*3)+(4*2)+(3*2)+(2*3)+(1*9)=149
149 % 10 = 9
So 851322-39-9 is a valid CAS Registry Number.
InChI:InChI=1/C16H22N2O/c19-15(14-4-2-1-3-5-14)18-12-8-16(9-13-18)6-10-17-11-7-16/h1-5,17H,6-13H2

851322-39-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,9-diazaspiro[5.5]undecan-3-yl(phenyl)methanone

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:851322-39-9 SDS

851322-39-9Downstream Products

851322-39-9Relevant academic research and scientific papers

NOVEL DIAZASPIROALKANES AND THEIR USE FOR TREATMENT OF CCR8 MEDIATED DISEASES

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Page/Page column 45-46, (2008/06/13)

The invention provides compounds of general formula. wherein A, B, W, X, Y, Z, D, E, R1 and n are as defined in the specification, processes for their preparation, pharmaceutical compositions containing them and their use in therapy.

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