851335-23-4Relevant academic research and scientific papers
Aluminum Chloride Mediated Alkynylation of Boron Subphthalocyanine Chloride Using Trimethylsilyl-Capped Acetylenes
Gotfredsen, Henrik,Jevric, Martyn,Broman, S?ren L.,Petersen, Anne U.,Nielsen, Mogens Br?ndsted
, p. 1 - 5 (2016)
A mild and versatile procedure is presented for functionalization of boron chloride subphthalocyanine at the axial boron position with trimethylsilyl-protected alkyne nucleophiles in the presence of aluminum chloride. The method allows a large variety of
AMINO ALCOHOL DERIVATIVE, MEDICINAL COMPOSITION CONTAINING THE SAME, AND USE OF THESE
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Page/Page column 36-37, (2008/06/13)
The present invention provides compounds represented by general formula (I): a prodrug thereof, or pharmaceutical acceptable salts thereof, wherein R1 is hydrogen or lower alkyl; each of R2 and R3 is independently hydrogen or lower alkyl; each of R4, R5 and R6 is independently hydrogen, halogen, lower alkyl or lower alkoxy; R7 is hydrogen or lower alkyl; R8 is hydrogen, halogen, lower alkyl, lower alkoxy, etc; R9 is -COR10, -A1-COR10, -O-A2-COR10, etc; Ar is optionally substituted phenyl or heteroaryl; and A is a bond, -OCH2-, etc, which exhibit potent and selective β3-adrenoceptor stimulating activities. The present invention also provides pharmaceutical compositions containing said compound, and uses thereof.
