851341-36-1

Usage

Uses

Used in Organic Chemistry:
1-Methoxymethoxy-2-(trifluoromethoxy)benzene is used as a reagent for the synthesis of various organic compounds, contributing to the creation of new molecules with diverse properties.
Used in Pharmaceutical Development:
In the pharmaceutical industry, 1-Methoxymethoxy-2-(trifluoromethoxy)benzene is used as a building block for the development of new drugs. Its unique functional groups and electron-withdrawing properties make it a valuable component in the design of molecules with specific therapeutic effects.
Used in Agrochemical Development:
Similarly, in the agrochemical industry, 1-Methoxymethoxy-2-(trifluoromethoxy)benzene is utilized as a building block for the development of new agrochemicals. Its properties can be harnessed to create molecules with targeted effects on pests or crops, enhancing agricultural productivity and crop protection.
It is crucial to handle 1-Methoxymethoxy-2-(trifluoromethoxy)benzene with care, as it can be hazardous if not used properly and in a controlled environment.

Upstream product

• 32858-93-8 2-(trifluoromethoxy)phenol 
• 107-30-2 chloromethyl methyl ether 

Downstream Products

• 1144501-89-2 1-(2-hydroxy-3-(trifluoromethoxy)phenyl)ethanone 
• 1285576-15-9 3-(3-cyano-4-methoxy-5-trifluoromethoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole 
• 1285576-13-7 3-(3-cyano-4-methoxy-5-trifluoromethoxybenzoyl)-2,3-dihydro-1,3-benzothiazole 
• 1285576-11-5 3-cyano-4-methoxy-5-trifluoromethoxybenzoyl chloride 
• 1285576-09-1 3-cyano-4-methoxy-5-trifluoromethoxybenzoic acid 
• 1285576-08-0 3-formyl-4-methoxy-5-trifluoromethoxybenzoic acid 
• 1285576-07-9 5-bromo-1-diethoxymethyl-2-methoxy-3-trifluoromethoxybenzene 
• 1285576-04-6 5-bromo-2-methoxy-3-trifluoromethoxybenzaldehyde 
• 497959-32-7 5-bromo-2-hydroxy-3-trifluoromethoxybenzaldehyde 
• 1285573-30-9 3-(3-cyano-4-hydroxy-5-trifluoromethoxybenzoyl)-1,1-dioxo-2,3-dihydro-1,3-benzothiazole 
• 497959-31-6 2-hydroxy-3-(trifluoromethoxy)benzaldehyde 
• 773873-50-0 2-hydroxy-3-(trifluoromethoxy)benzoic acid 

Relevant academic research and scientific papers

TRPV1 Antagonists

Disclosed herein are compounds of formula (I): or pharmaceutically acceptable salts thereof, wherein X1, L, Rx, Ry, Rz, A, m, n, p, q, s, and positions a and b are as defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

NOVEL PHENOL DERIVATIVE

Disclosed are a novel compound and a pharmaceutical product, each having a remarkable uricosuric effect. Specifically disclosed are: a novel phenol derivative represented by general formula (1) that is shown in FIG. 1; a pharmaceutically acceptable salt t

TRPV1 ANTAGONISTS

Disclosed herein are compounds of Formula (I), or pharmaceutically acceptable salts, solvates, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, R4, and m are defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

TRPV1 ANTAGONISTS

Disclosed herein are compounds of formula (I), or pharmaceutically acceptable salts, solvates, prodrugs, salts of prodrugs, or combinations thereof, wherein R1, R2, R3, R4, and m are defined in the specification. Compositions comprising such compounds and methods for treating conditions and disorders using such compounds and compositions are also disclosed.

The site-selective functionalization of halogen-bearing phenols: An exercise in diversity-oriented organometallic synthesis

The organometallic approach to diversity-oriented organic synthesis was subjected to a further test, this time in the phenol series. The model compounds selected were 2,3,6-trifluorophenol, the three isomers of (trifluoromethoxy) phenol and the three isomers of chlorophenol. A combination of optionally site selective metalations and protective group-controlled metalations enabled the selective generation of several isomeric intermediates in each case and their subsequent conversion into functionalized derivatives, in particular hydroxybenzoic acids.