851371-16-9

Upstream product

• 696-63-9 4-Methoxybenzenethiol 
• 1318254-52-2 (R)-ethyl 3-(4-methoxyphenylthio)-4,4,4-trifluorobutanoate 

Downstream Products

• 851371-15-8 N-benzyloxy-4,4,4-trifluoro-3-(4-methoxy-phenylsulfanyl)-butyramide 

Relevant academic research and scientific papers

Organocatalytic asymmetric Sulfa-Michael addition of thiols to 4,4,4-trifluorocrotonates

The first asymmetric sulfa-Michael addition of thiols to 4,4,4-trifluorocrotonates for the construction of a stereogenic center bearing a unique trifluoromethyl group and a sulfur atom has been achieved in high yields and excellent enantioselectivities wi

Novel highly potent, structurally simple γ-trifluoromethyl γ-sulfone hydroxamate inhibitor of stromelysin-1 (MMP-3)

The γ-trifluoromethyl γ-sulfone hydroxamate 1 was synthesized both in racemic and enantiomerically pure forms by means of a thia-Michael reaction of p-methoxythiophenol on achiral and chiral 3,3,3-trifluorocrotonoyl Michael acceptors. The (R)-1 enantiomer