85142-93-4Relevant academic research and scientific papers
Catalyst-Free Insertion of Sulfoxonium Ylides into Aryl Thiols. A Direct Preparation of β-Keto Thioethers
Dias, Rafael M. P.,Burtoloso, Antonio C. B.
, p. 3034 - 3037 (2016)
Insertion of sulfoxonium ylides into the S-H bond of aryl thiols without the need for a catalyst is demonstrated, furnishing β-keto thioethers in excellent yield in most cases. The method overcomes traditional syntheses that employ metal catalysts in combination with diazo compounds or toxic and hard-prepared haloketones. The experimental setup consists of mixing the reagents in acetonitrile at room temperature. Additional experimental as well as kinetic isotopic effect studies give some insight into the mechanism of this reaction.
Electrocatalytic Synthesis of gem -Bisarylthio Enamines and α-Phenylthio Ketones via a Radical Process under Mild Conditions
Pan, Yong-Zhou,Cheng, Shi-Yan,Li, Qian-Yu,Tang, Hai-Tao,Pan, Ying-Ming,Meng, Xiu-Jin,Mo, Zu-Yu
, p. 593 - 600 (2021/03/17)
The novel method for the synthesis of gem -bisarylthio enamines and α-phenylthio ketones was developed via the coupling of α-substituted vinyl azides with thiols in the presence of tetrabutylammonium iodide (TBAI) as a redox catalyst and electrolyte at ro
