851478-84-7

Basic information

• Product Name: (4-hydroxy-phenylsulfanyl)-acetic acid 2-morpholin-4-yl-2-oxo-ethyl ester
• Synonyms: (4-hydroxy-phenylsulfanyl)-acetic acid 2-morpholin-4-yl-2-oxo-ethyl ester
• CAS NO: 851478-84-7
• Molecular Weight: 311.359
• Mol File: 851478-84-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-hydroxy-phenylsulfanyl)-acetic acid 2-morpholin-4-yl-2-oxo-ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (4-hydroxy-phenylsulfanyl)-acetic acid 2-morpholin-4-yl-2-oxo-ethyl ester(851478-84-7)
• EPA Substance Registry System: (4-hydroxy-phenylsulfanyl)-acetic acid 2-morpholin-4-yl-2-oxo-ethyl ester(851478-84-7)

Safety Data

• Hazardous Substances Data: 851478-84-7(Hazardous Substances Data)

Upstream product

• 28743-98-8 (4-methoxy-phenylsulfanyl)-acetic acid ethyl ester 
• 696-63-9 4-Methoxybenzenethiol 

Relevant articles and documents

Synthesis and structure-activity relationship study of the new set of trypsin-like proteinase inhibitors

A new set of 25 trypsin-like proteinase inhibitors was prepared and the inhibiting activity on trypsin, thrombin, plasmin and urokinase was measured. The structure-activity relationship is discussed. High inhibiting activities were observed in 4-guanidinobenzoic acid esters only. The replacement of this moiety for N-formamidinyl-isonipecotic acid or an arginine moiety caused almost total loss of the activity. In the series of 4-guanidinobenzoic acid esters, any important influence of the ester-groups reactivity was observed. The trypsin-thrombin selectivity in the compounds with the guanidine-remote carboxylic function was also observed.