851531-15-2Relevant academic research and scientific papers
Cobalt-Catalyzed Enantioselective Hydroarylation of 1,6-Enynes
Whyte, Andrew,Torelli, Alexa,Mirabi, Bijan,Prieto, Liher,Rodríguez, José F.,Lautens, Mark
, p. 9510 - 9517 (2020/05/18)
An asymmetric hydroarylative cyclization of enynes involving a C-H bond cleavage is reported. The cobalt-catalyzed cascade generates three new bonds in an atom-economical fashion. The products were obtained in excellent yields and excellent enantioselectivities as single diastereo- and regioisomers. Preliminary mechanistic studies indicate that the reaction shows no intermolecular C-H crossover. This work highlights the potential of cobalt catalysis in C-H bond functionalization and enantioselective domino reactivity.
Atom-Economical Ni-Catalyzed Diborylative Cyclization of Enynes: Preparation of Unsymmetrical Diboronates
Cabrera-Lobera, Natalia,Quirós, M. Teresa,Brennessel, William W.,Neidig, Michael L.,Bu?uel, Elena,Cárdenas, Diego J.
, p. 6552 - 6556 (2019/08/20)
We report a Ni-catalyzed diborylative cyclization of enynes that affords carbo- and heterocycles containing both alkyl- and alkenylboronates. The reaction is fully atom-economical, shows a broad scope, and employs a powerful and inexpensive catalytic Ni-b
Ni-Catalyzed Cyclization of Enynes and Alkynylboronates: Atom-Economical Synthesis of Boryl-1,4-dienes
Cabrera-Lobera, Natalia,Quirós, M. Teresa,Bu?uel, Elena,Cárdenas, Diego J.
, p. 14512 - 14516 (2019/11/11)
We report a novel atom-economical Ni-catalyzed cyclization reaction of enynes with alkynylboronates. The reaction employs a non-expensive Ni salt, a phosphine-based ligand and easy-handling alkynylboronates as boron–carbon source. The reaction provides co
Iron-Catalyzed Hydroborylative Cyclization of 1,6-Enynes
Cabrera-Lobera, Natalia,Rodríguez-Salamanca, Patricia,Nieto-Carmona, Juan C.,Bu?uel, Elena,Cárdenas, Diego J.
, p. 784 - 788 (2017/11/29)
We report first Fe-catalyzed hydroborylative cyclization reaction. The process provides one C?C and one C?B bond in a single operation and shows a wide scope, allowing the formation of carbo- and heterocycles containing a homoallylic boryl unit that can b
Ligand Control of E/Z Selectivity in Nickel-Catalyzed Transfer Hydrogenative Alkyne Semireduction
Richmond, Edward,Moran, Joseph
, p. 6922 - 6929 (2015/10/05)
A nickel-catalyzed transfer hydrogenative alkyne semireduction protocol that can be applied to both internal and terminal alkynes using formic acid and Zn as the terminal reductants has been developed. In the case of internal alkynes, the (E)- or (Z)-olefin isomer can be accessed selectively under the same reaction conditions by judicious inclusion of a triphos ligand.
Iron-catalyzed reductive cyclization of 1,6-enynes
Lin, Aijun,Zhang, Zhi-Wei,Yang, Jiong
supporting information, p. 386 - 389 (2014/04/03)
A precatalyst of FeCl2 and iminopyridine was activated in situ by a combination of diethylzinc and magnesium bromide etherate; it catalyzed the reductive cyclization of 1,6-enynes to give pyrrolidine and tetrahydrofuran derivatives from N-and O
Thioureas as ligands in the Pd-catalyzed intramolecular Pauson-Khand reaction
Tang, Yefeng,Deng, Lujiang,Zhang, Yangdong,Dong, Guangbin,Chen, Jiahua,Yang, Zhen
, p. 1657 - 1659 (2007/10/03)
(Chemical Equation Presented) The thiourea-Pd complex was established as a novel type of catalyst in the PKR of allylpropargylamine, and the demonstrated chemistry may prove to be valuable for developing thiuorea as a ligand for the Pd-catalyzed Pauson-Kh
