851581-26-5

Basic information

• Product Name: [4-(ethoxycarbonyl)-1,3-thiazol-2-yl]methyl 5-({[(benzyloxy)carbonyl]amino}methyl)-6-isobutyl-2-methyl-4-(4-methylphenyl)nicotinate
• Synonyms: [4-(ethoxycarbonyl)-1,3-thiazol-2-yl]methyl 5-({[(benzyloxy)carbonyl]amino}methyl)-6-isobutyl-2-methyl-4-(4-methylphenyl)nicotinate
• CAS NO: 851581-26-5
• Molecular Weight: 615.75
• Mol File: 851581-26-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: [4-(ethoxycarbonyl)-1,3-thiazol-2-yl]methyl 5-({[(benzyloxy)carbonyl]amino}methyl)-6-isobutyl-2-methyl-4-(4-methylphenyl)nicotinate(CAS DataBase Reference)
• NIST Chemistry Reference: [4-(ethoxycarbonyl)-1,3-thiazol-2-yl]methyl 5-({[(benzyloxy)carbonyl]amino}methyl)-6-isobutyl-2-methyl-4-(4-methylphenyl)nicotinate(851581-26-5)
• EPA Substance Registry System: [4-(ethoxycarbonyl)-1,3-thiazol-2-yl]methyl 5-({[(benzyloxy)carbonyl]amino}methyl)-6-isobutyl-2-methyl-4-(4-methylphenyl)nicotinate(851581-26-5)

Safety Data

• Hazardous Substances Data: 851581-26-5(Hazardous Substances Data)

Upstream product

• 851581-25-4 2-amino-2-thioxoethyl 5-({[(benzyloxy)carbonyl]amino}methyl)-6-isobutyl-2-methyl-4-(4-methylphenyl)nicotinate 
• 70-23-5 ethyl Bromopyruvate 

Downstream Products

• 851581-27-6 [4-(ethoxycarbonyl)-1,3-thiazol-2-yl]methyl 5-{[(tert-butoxycarbonyl)amino]methyl}-6-isobutyl-2-methyl-4-(4-methylphenyl)nicotinate 

Relevant articles and documents

PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV

A compound represented by the formula wherein R1 and R2 are the same or different and each is an optionally substituted hydrocarbon group or an optionally substituted hydroxy group; R3 is an optionally substituted aromatic group; R4 is an optionally substituted amino group; L is a divalent chain hydrocarbon group; Q is a bond or a divalent chain hydrocarbon group; and X is a hydrogen atom, a cyano group, a nitro group, an acyl group, a substituted hydroxy group, an optionally substituted thiol group, an optionally substituted amino group or an optionally substituted cyclic group; provided that when X is an ethoxycarbonyl group, then Q is a divalent chain hydrocarbon group. The compound has a peptidase inhibitory action, is useful as an agent for the prophylaxis or treatment of diabetes and the like, and is superior in efficacy, duration of action, specificity, lower toxicity and the like.