851581-65-2

Usage

Uses

Used in Pharmaceutical Synthesis:
(E)-1-(3-bromophenyl)-3-(p-tolyl)prop-2-en-1-one is used as an intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique chemical structure allows for the creation of new pharmaceutical compounds that can address a range of health conditions.
Used in Agrochemical Production:
In the agrochemical industry, (E)-1-(3-bromophenyl)-3-(p-tolyl)prop-2-en-1-one is utilized as a key intermediate in the production of different agrochemicals. Its chemical properties make it suitable for the development of compounds that can be used in agriculture to enhance crop protection and yield.
Used in Organic Chemistry Research:
(E)-1-(3-bromophenyl)-3-(p-tolyl)prop-2-en-1-one is also employed in the field of organic chemistry research. Its distinctive structure provides researchers with a versatile compound to explore new reactions and mechanisms, potentially leading to the discovery of novel chemical products and materials.
Used in Chemical Product Development:
(E)-1-(3-bromophenyl)-3-(p-tolyl)prop-2-en-1-one is used as a building block in the development of various chemical products. Its unique structure and properties make it an attractive candidate for the creation of new materials with specific applications in different industries, such as coatings, adhesives, and polymers.

Upstream product

• 104-87-0 4-methyl-benzaldehyde 
• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 622-97-9 1-ethenyl-4-methylbenzene 
• 7194-78-7 (3-bromophenyl)oxoacetic acid 

Downstream Products

• 1061342-84-4 C₁₇H₁₆BrN₃S 

Relevant academic research and scientific papers

Domino-Fluorination-Protodefluorination Enables Decarboxylative Cross-Coupling of α-Oxocarboxylic Acids with Styrene via Photoredox Catalysis

Domino-fluorination-protodefluorination decarboxylative cross-coupling of α-keto acids with styrene has been developed via photoredox catalysis. The critical part of this strategy is the formation of the carbon-fluorine (C-F) bond by the capture of a carbon-centered radical intermediate, which will overcome side reactions during the styrene radical functionalization process. Experimental studies have provided evidence indicating a domino-fluorination-protodefluorination pathway with α-keto acid initiating the photoredox cycle. The present catalytic protocol also affords a novel approach for the construction of α,β-unsaturated ketones under mild conditions.

Syntheses and evaluation of 3-(3-bromo phenyl)-5-phenyl-1-(thiazolo [4,5-b] quinoxaline-2-yl)-2-pyrazoline derivatives

A variety of 3-(3-bromo phenyl)-5-phenyl-1-(thiazolo [4,5-b] quinoxaline-2-yl)-2-pyrazoline were obtained by the refluxing of 1-N-thiocarbamoyl 3,5-diphenyl-2-pyrazoline with 2,3-dichloroquinoxaline. The chemical structures of the compounds were elucidated by UV, IR, 1H NMR, and 13C NMR spectroscopy. The purity of the compounds was confirmed by their elemental analysis. The antiamoebic activity of these compounds was evaluated by microdilution method against HMI:IMSS strain of Entamoeba histolytica and the IC50 values were compared with the standard drug metronidazole. Some of the quinoxaline derivatives showed less IC50 values than metronidazole. To elucidate the toxic effect, MTT assay was performed using kidney epithelial cell line. The results showed that all the compounds are non-toxic.

PYRIDINE COMPOUNDS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE IV

A compound represented by the formula wherein R1 and R2 are the same or different and each is an optionally substituted hydrocarbon group or an optionally substituted hydroxy group; R3 is an optionally substituted aromatic group; R4 is an optionally substituted amino group; L is a divalent chain hydrocarbon group; Q is a bond or a divalent chain hydrocarbon group; and X is a hydrogen atom, a cyano group, a nitro group, an acyl group, a substituted hydroxy group, an optionally substituted thiol group, an optionally substituted amino group or an optionally substituted cyclic group; provided that when X is an ethoxycarbonyl group, then Q is a divalent chain hydrocarbon group. The compound has a peptidase inhibitory action, is useful as an agent for the prophylaxis or treatment of diabetes and the like, and is superior in efficacy, duration of action, specificity, lower toxicity and the like.