851592-00-2

Upstream product

• 851592-12-6 trans-(2R)-1-(tert-butyldimethylsilyloxy)-3,4-epoxy-6-phenylhexan-2-ol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 851592-11-5 (3E)-(2S)-1-(tert-butyldimethylsilyloxy)-6-phenylhex-3-en-2-ol 
• 851592-10-4 (3E)-(2S)-6-phenylhex-3-ene-1,2-diol 
• 851592-02-4 (4R)-2,2-dimethyl-4-[(1Z)-4-phenylbut-1-enyl]-1,3-dioxolane 
• 851592-03-5 (4R)-2,2-dimethyl-4-[(1E)-4-phenylbut-1-enyl]-1,3-dioxolane 

Downstream Products

• 851592-17-1 (1R,2R,1'S,2'S)-1-(trans-2'-phenylcyclopropyl)-1,3-di-tert-butyldimethylsilyloxypropan-2-ol 
• 851592-16-0 (1R,2R,1'S,2'S)-1-(trans-2'-phenylcyclopropyl)-2,3-di-tert-butyldimethylsilyloxy-propan-1-ol 

Relevant academic research and scientific papers

Superbase-promoted rearrangement of oxiranes to cyclopropanes

Aryl- and alkenyl substituted oxiranes, when submitted to treatment with superbasic reagents, undergo a highly regio- and stereoselective rearrangement leading to cyclopropylmethanol derivatives. The process can also be applied to mono- and dihydroxy subs