851593-75-4Relevant academic research and scientific papers
An efficient synthesis of cyclic β-amino acid derivatives as β-turn mimetics
Yamanaka, Toshio,Ohkubo, Mitsuru,Kato, Masayuki,Kawamura, Yasufumi,Nishi, Akinori,Hosokawa, Takahiro
, p. 631 - 634 (2007/10/03)
Seven-, eight-, and nine-membered cyclic β-amino acids, precursors of platelet aggregation inhibitors, were synthesized for the first time starting from N-alkenyl amines and ethyl acrylate via ring-closing metathesis (RCM) as the key reaction. Synthesis o
