851636-82-3

Upstream product

• 851636-68-5 (3aS,4S,6R,6aR)-6-(6-Benzoylamino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxole-4-carbonyl chloride 
• 119750-97-9 N⁶-benzoyl-2',3'-isopropylidene-5'-carboxylic acid-5'-deoxy-adenosine 
• 811431-31-9 N-[9-(6-diazoacetyl-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-9H-purin-6-yl]-benzamide 

Downstream Products

• 811431-33-1 [(3aR,4R,6R,6aR)-6-(6-Amino-purin-9-yl)-2,2-dimethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl]-acetic acid 

Relevant academic research and scientific papers

Inactivation of S-adenosylhomocysteine hydrolase with haloethyl and dihalocyclopropyl esters derived from homoadenosine-6′-carboxylic acid

Inactivation of AdoHcy hydrolase with 2-3 resulted in time-dependent loss of enzyme activity. The mechanism of inactivation is discussed. In a search for new inhibitors that exploit 5′-6′ 'hydrolytic activity' of AdoHcy hydrolase, a new series of haloethy