851702-45-9Relevant academic research and scientific papers
Synthesis, single crystal structure and efficient catalysis for alcohol oxidation of a novel Ru(II) complex with both a N,N,N-tridentate ligand and a pyridinedicarboxylate
Zhang, Yuecheng,Liu, Liu,Cao, Xiaohui,Zhao, Jiquan
, p. 170 - 177 (2016)
A novel N,N,N-tridentate ligand known as 2-(2-pyridylmethylamino)ethylbenzimidazole (pymaeb) was designed and synthesized. This ligand in combination with disodium pyridine-2,6-dicarboxylate (pydic) reacted with RuCl3 to afford a novel complex Ru[2-(2-pyridymethylimino)ethylbenzimidazole]pyridinedicarboxylate [Ru(pymieb)(pydic)] which was characterized by NMR, IR, HR-MS and single crystal X-ray diffraction. Crystal structure analysis revealed that the complex has a distorted octahedral geometry. The complex showed excellent activity for the oxidation of various alcohols with TBHP as oxidation under mild and solvent-free conditions.
Structural features and functional activities of benzimidazoles as NOD2 antagonists
Guzelj, Samo,Gobec, Martina,Urban?i?, Dunja,Mlinari?-Ra??an, Irena,Corsini, Emanuela,Jakopin, ?iga
, (2020/02/04)
NOD1 and NOD2 are pattern recognition receptors that have important roles in innate immune responses. Although their overactivation has been linked to a number of diseases, NOD2 in particular remains a virtually unexploited target in this respect, with on
BENZIMIDAZOLES USEFUL AS MODULATORS OF ION CHANNELS
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Page/Page column 220-221, (2008/06/13)
The present invention relates to compounds of Formula I: or a pharmaceutically acceptable salt thereof, wherein the R1, Z, Y, RA, and W groups of formula I are as defined herein. The invention also provides pharmaceutically acceptable compositions and met
Evaluation of the Dmt-Tic pharmacophore: Conversion of a potent δ-opioid receptor antagonist into a potent δ agonist and ligands with mixed properties
Balboni, Gianfranco,Guerrini, Remo,Salvadori, Severo,Bianchi, Clementina,Rizzi, Daniela,Bryant, Sharon D.,Lazarus, Lawrence H.
, p. 713 - 720 (2007/10/03)
Analogues of the 2′,6′-dimethyl-L-tyrosine (Dmt)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid (Tic) pharmacophore were prepared to test the hypothesis that a "spacer" and a third aromatic center in opioid peptides are required to convert a δ-antagonis
