851756-49-5Relevant academic research and scientific papers
Structure-activity relationships for 2-anilino-6-phenylpyrido[2,3-d] pyrimidin-7(8H)-ones as inhibitors of the cellular checkpoint kinase Wee1
Palmer, Brian D.,Smaill, Jeff B.,Rewcastle, Gordon W.,Dobrusin, Ellen M.,Kraker, Alan,Moore, Charles W.,Steinkampf, Randall W.,Denny, William A.
, p. 1931 - 1935 (2005)
A series of 2-anilino-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-ones were synthesized and evaluated for their inhibitory properties against the non-receptor kinase c-Src and the G2/M checkpoint kinase Wee1. Overall, the compounds were 10-100-fold more potent i
