851784-78-6 Usage
Structure
2(1H)-isoquinolinecarboxylic acid, 5,7-dichloro-3,4-dihydro-6-[[(trifluoromethyl)sulfonyl]oxy], 1,1-dimethylethyl ester
Tert-butyl ester derivative
5,7-dichloro-3,4-dihydroisoquinoline-2(1H)-carboxylic acid
Potential anti-cancer agent
The compound has shown potential as an anti-cancer agent in preclinical studies.
Pharmacological and biological activities
The compound has potential pharmacological and biological activities that can be useful in the development of new pharmaceuticals.
Trifluoromethylsulfonyl group
The presence of the trifluoromethylsulfonyl group is known for enhancing the potency and selectivity of certain drugs.
Medicinal chemistry research
The compound is used in medicinal chemistry research for the development of new pharmaceuticals with improved potency and efficacy.
Check Digit Verification of cas no
The CAS Registry Mumber 851784-78-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,1,7,8 and 4 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 851784-78:
(8*8)+(7*5)+(6*1)+(5*7)+(4*8)+(3*4)+(2*7)+(1*8)=206
206 % 10 = 6
So 851784-78-6 is a valid CAS Registry Number.
851784-78-6Relevant articles and documents
LFA-1 INHIBITOR AND POLYMORPH THEREOF
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, (2014/02/16)
Methods of preparation and purification of a compound, intermediates thereof, a polymorph thereof, and related compounds are disclosed. Formulations and uses thereof in the treatment of LFA -1 mediated diseases are also disclosed.
MODULATORS OF CELLULAR ADHESION
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Page/Page column 76-78, (2010/02/11)
The present invention provides compounds having formula (I): and pharmaceutically acceptable derivatives thereof, wherein R1-R4, n, p, A, B, D, E, L and AR1 are as described generally and in classes and subclasses herein, and additionally provides pharmaceutical compositions thereof, and methods for the use thereof for the treatment of disorders mediated by the CD11/CD18 family of cellular adhesion molecules (e.g., LFA-1).
