851854-84-7

Basic information

• Product Name: (RS)-4-(6-methylpyridin-2-yl)but-3-yn-2-ol
• Synonyms: (RS)-4-(6-methylpyridin-2-yl)but-3-yn-2-ol
• CAS NO: 851854-84-7
• Molecular Formula: C₁₀H₁₁NO
• Molecular Weight: 161
• Mol File: 851854-84-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (RS)-4-(6-methylpyridin-2-yl)but-3-yn-2-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (RS)-4-(6-methylpyridin-2-yl)but-3-yn-2-ol(851854-84-7)
• EPA Substance Registry System: (RS)-4-(6-methylpyridin-2-yl)but-3-yn-2-ol(851854-84-7)

Safety Data

• Hazardous Substances Data: 851854-84-7(Hazardous Substances Data)

Upstream product

• 5315-25-3 2-bromo-6-methylpyridine 
• 2028-63-9 but-3-yn-2-ol 

Relevant articles and documents

Structure-activity relationships for the linker in a series of pyridinyl-alkynes that are antagonists of the metabotropic glutamate receptor 5 (mGluR5)

Studies of structure-activity relationships for the linker in a new series of metabotropic glutamate receptor 5 antagonists are presented together with in vitro and in vivo pharmacokinetic data.

ALKYNES III

The present invention is directed to novel compounds of formula 1, to a process, for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds. The novel compounds are useful in therapy, and in particular for t