851908-94-6

Upstream product

• 659726-50-8 tert-butyl (2S)-2-[N-(9-phenylfluoren-9-yl)amino]pent-4-enoate 
• 410098-01-0 (2S)-2-aminohex-5-enoic acid methyl ester 
• 613-45-6 2,4-Dimethoxybenzaldehyde 
• 146549-21-5 2-(9H-fluoren-9-ylmethoxycarbonylamino)-pent-4-enoic acid 
• 851909-11-0 methyl (2S)-2-[(2,4-dimethoxybenzyl)amino]hex-5-enoate 
• 851909-01-8 N-(N-(Fmoc)-L-allylglycyl)-N-(2,4-dimethoxybenzyl)-L-homoallylglycine methyl ester 

Relevant academic research and scientific papers

Systematic study of the synthesis of macrocyclic dipeptide β-turn mimics possessing 8-, 9-, and 10- membered rings by ring-closing metathesis

A systematic study was performed to establish general synthesis protocols for forming enantiomerically pure macrocyclic dipeptide lactams. Focusing on macrocycles of 8-, 9-, and 10-membered rings, effective syntheses were achieved by a sequence featuring