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• 108-24-7 acetic anhydride 
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• 610-97-9 o-iodo-methyl-benzoic acid 

Relevant academic research and scientific papers

An asymmetric biaryl Suzuki cross-coupling reaction: Stereogenic benzylic carbinols as chiral auxiliaries

Asymmetric biaryl Suzuki coupling reactions were performed with various aryl- or naphthylhalide-bearing enantiomerically pure benzylic alcohols and aryl- or naphthylboronic acids (or esters). The stereogenic benzylic alcohol was introduced by diastereoselective reduction of the arylhalide bearing a β-keto sulfoxide. In the presence of Pd(OAc)2/CsF and dppf or PPh3 excellent yields and atropodiastereoselectivities were obtained. The absolute configurations of the biaryls were determined by X-ray crystallography and 1H NMR NOESY experiments. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005.