851935-75-6Relevant academic research and scientific papers
Synthesis of 5′-methylenearisteromycin and its 2-fluoro derivative with potent antimalarial activity due to inhibition of the parasite S-adenosylhomocysteine hydrolase
Takagi, Chieko,Sukeda, Makoto,Kim, Hye-Sook,Wataya, Yusuke,Yabe, Saori,Kitade, Yukio,Matsuda, Akira,Shuto, Satoshi
, p. 1245 - 1251 (2007/10/03)
5′-Methylenearisteromycin (5) and its 2-fluoro derivative 6, which were designed as antimalarial agents because of their AdoHcy hydrolase inhibition, were synthesized from D-ribose, using a stereoselective intramolecular radical cyclization as the key ste
