85195-24-0Relevant academic research and scientific papers
Methyl N-(benzylsulfonyl)oxamate as a probable intermediate in the synthesis of 4-hydroxy-5-phenyl-3(2H)-isothiazolone 1,1-dioxide from phenylmethanesulfamide and dimethyl oxalate in the presence of bases
Zlotin, S. G.,Gerasyuto, A. I.
, p. 394 - 395 (1999)
The formation of 4-hydroxy-5-phenyl-3(2H)-isothiazolone 1,1-dioxide from phenylmethanesulfamide and dimethyl oxalate under the action of bases is apparently a two-stage process involving the formation of linear methyl N-(benzylsulfonyl)oxamate followed by
Diamino isothiazole-1-oxides and 1,1 dioxides as gastric secretion inhibitors
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, (2008/06/13)
This invention is directed to diamino isothiazole -1-oxides and -1,1-dioxides and related compounds as well as pharmaceutical compositions and methods useful in the treatment of gastric secretion in mammals.
5-Aryl-4-hydroxy-3(2H)-isothiazolone 1,1-Dioxide Derivatives. Synthesis and 13C NMR Characterization
Rooney, C. S.,Cochran, D. W.,Ziegler, C.,Cragoe, E. J.,Williams, H. W. R.
, p. 2212 - 2217 (2007/10/02)
5-Phenyl- and 5-thiazolyl-4-hydroxy-3(2H)-isothiazolone 1,1-dioxide derivatives have been prepared by base-catalyzed cyclocondensation of diethyl oxalate with an arylmethanesulfonamide, as well as by reaction of an arylmethanesulfonamide with methyl or et
4-Hydroxy-5-substituted-3-(2H)-isothiazolone-1,1-dioxide derivatives useful in treating urinary tract calcium oxalate lithiasis
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, (2008/06/13)
4-Hydroxy-5-substituted-3(2H)-isothiazolone-1,1-dioxide derivatives of the formula: STR1 where X and Y are independently selected from the group consisting of hydrogen, halogen, and C1-6 alkyl; provided that positions 2 and 6 of the substituted
