851963-22-9Relevant academic research and scientific papers
Hybrid solution/solid-phase synthesis of oligosaccharides by using trichloroacetyl isocyanate as sequestration-enabling reagent of sugar alcohols
Dondoni, Alessandro,Marra, Alberto,Massi, Alessandro
, p. 1672 - 1676 (2007/10/03)
(Chemical Equation Presented) An excess of glycosyl acceptor is used in the solution-phase synthesis of oligosaccharides and any unconverted acceptor is removed by using trichloroacetyl isocyanate. A levulinoyl (Lev) ester group is then used as a masked tag in the following "resin-capture-release" purification strategy (see scheme).
