851985-87-0

Basic information

• Product Name: 3-methyl-7-Quinolinol
• Synonyms: 3-methyl-7-Quinolinol;3-methylquinolin-7-ol
• CAS NO: 851985-87-0
• Molecular Formula: C10H9NO
• Molecular Weight: 159.18456
• Mol File: 851985-87-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-methyl-7-Quinolinol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-7-Quinolinol(851985-87-0)
• EPA Substance Registry System: 3-methyl-7-Quinolinol(851985-87-0)

Safety Data

• Hazardous Substances Data: 851985-87-0(Hazardous Substances Data)

Usage

Description

3-methyl-7-Quinolinol, also known as 3-methyl-7-hydroxyquinoline or 3-methylquinolin-7-ol, is a quinoline derivative with a molecular formula of C10H9NO. It features a hydroxyl group at the 7th position and a methyl group at the 3rd position, giving it a yellow to orange color. This versatile organic reagent is utilized in the synthesis of pharmaceutical and agrochemical compounds, and its antimicrobial, antiviral, and antioxidant properties make it a promising candidate for new drug and medical treatment development. Furthermore, it finds applications in dye manufacturing and as a corrosion inhibitor in industrial settings.

Uses

Used in Pharmaceutical and Agrochemical Industries:
3-methyl-7-Quinolinol is used as a key intermediate in the synthesis of various pharmaceutical and agrochemical compounds, contributing to the development of new drugs and pesticides.
Used in Antimicrobial Applications:
3-methyl-7-Quinolinol is used as an antimicrobial agent, leveraging its ability to inhibit the growth of harmful microorganisms, which is beneficial in medical treatments and sanitization processes.
Used in Antiviral Applications:
3-methyl-7-Quinolinol is used as an antiviral agent, helping to combat viral infections and contributing to the development of treatments for various viral diseases.
Used in Antioxidant Formulations:
3-methyl-7-Quinolinol is used as an antioxidant, protecting against oxidative stress and damage, which is important in both medical and industrial applications.
Used in Dye Manufacturing:
3-methyl-7-Quinolinol is used as a component in the production of dyes, capitalizing on its color properties to create a range of dye products.
Used in Corrosion Inhibition:
3-methyl-7-Quinolinol is used as a corrosion inhibitor in industrial applications, helping to protect materials from degradation and extending their service life.

Upstream product

• 851985-86-9 7-methoxy-3-methylquinoline 

Relevant articles and documents

SUBSTITUTED NITROGEN-CONTAINING SIX-MEMBERED AMINO-HETEROCYCLES AS VANILLOID-1 RECEPTOR ANTAGONISTS FOR TREATING PAIN

The present invention provides a compound of formula (I): Y-J-NH-Z wherein: Y is a quinoline or isoquinoline optionally substituted with one or two substituents independently chosen from hydroxy, halogen, haloC1-4alkyl, C1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, nitro and amino; J is pyridine, pyridazine, pyrazine, pyrimidine or triazine optionally substituted with one or two substituents independently chosen from hydroxy, halogen, haloC1-4alkyl, C1-4alkyl, C3-5cycloalkyl, C1-4alkoxy, hydroxyC1-4alkyl, cyano, hydroxy, C1-4cycloalkoxy, C1-4alkylthio, haloC1-4alkoxy, nitro, Q, (CH2)pQ, NR2R3, -(CH2)pNR2R3 and -O(CH2)pNR2R3; wherein J is substituted at positions meta to each other by NH and Y; and Z is phenyl or pyridyl optionally substituted with one or two substituents independently selected from halogen, haloC1-4alkyl, C1-4alkyl, C1-4alkoxy, haloC1-4alkoxy, nitro and amino; Q is phenyl, a five-membered heterocyclic ring containing one, two, three or four heteroatoms chosen from O, N and S, at most one heteroatom being O or S, or a six-membered heterocyclic ring containing one, two or three nitrogen atoms, optionally substituted by C1-4alkyl; each R2 and R3 is chosen from H and C1-4alkyl, or R2 and R3, together with the nitrogen atom to which they are attached, may form a six-membered ring optionally containing an oxygen atom or a further nitrogen atom, which ring is optionally substituted by C1-4alkyl or Q; p is 1, 2 or 3; or a pharmaceutically acceptable salt thereof; pharmaceutical compositions comprising it; its use in methods of therapy; use of it for manufacturing medicaments; and methods of using it to treat diseases requiring administration of a VR1 antagonist such as pain, cough, GERD and depression.