852061-94-0

Basic information

• Product Name: 7-Bromo-5-fluoro-quinoline
• Synonyms: 7-Bromo-5-fluoro-quinoline
• CAS NO: 852061-94-0
• Molecular Formula: C9H5BrFN
• Molecular Weight: 226.0451032
• Mol File: 852061-94-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 294.9±20.0 °C(Predicted)
• Appearance: /
• Density: 1.647±0.06 g/cm3(Predicted)
• PKA: 2.43±0.26(Predicted)
• CAS DataBase Reference: 7-Bromo-5-fluoro-quinoline(CAS DataBase Reference)
• NIST Chemistry Reference: 7-Bromo-5-fluoro-quinoline(852061-94-0)
• EPA Substance Registry System: 7-Bromo-5-fluoro-quinoline(852061-94-0)

Safety Data

• Hazardous Substances Data: 852061-94-0(Hazardous Substances Data)

Usage

General Description

7-Bromo-5-fluoro-quinoline is a chemical compound with the molecular formula C9H5BrFNO. It is a fluorinated quinoline derivative featuring a bromine substituent at the 7-position and a fluorine substituent at the 5-position of the quinoline ring. 7-Bromo-5-fluoro-quinoline is of interest in pharmaceutical and agrochemical research due to its potential as a building block in the synthesis of biologically active compounds. It has been used in the development of antimalarial and antibacterial agents, and as a fluorescent probe for studying cellular processes. Additionally, it has been investigated for its potential applications in materials science and as a ligand in coordination chemistry. As such, 7-Bromo-5-fluoro-quinoline is a versatile compound with diverse uses in various scientific disciplines.

Upstream product

• 134168-98-2 3-bromo-5-fluoroaniline hydrochloride 
• 56-81-5 glycerol 

Relevant articles and documents

ALPHA, BETA-UNSATURATED AMIDE COMPOUND

An object of the present invention is to provide an α,β-unsaturated amide compound or a pharmaceutically acceptable salt or the like thereof having anticancer activity and the like. The α,β-unsaturated amide compound represented by the following formula (I) or a pharmaceutically acceptable salt or the like thereof has anticancer activity and the like: [wherein, "A" represents optionally substituted heterocyclic diyl, R1 represents hydrogen atom or optionally substituted lower alkyl, R2 represents optionally substituted aryl, optionally substituted cycloalkyl, optionally substituted aliphatic heterocyclic group or optionally substituted aromatic heterocyclic group, X represents -O-, -S-, -SO2-, -NRX1- (wherein, RX1 represents hydrogen atom or lower alkyl), -CHRX2- (wherein, RX2 represents hydrogen atom or hydroxy), -CH=CH-, -CO- or -NH-CO-, and n1 and n2 are the same or different, and each represents 0 or 1].

INHIBITORS OF JUN N-TERMINAL KINASE

The present disclosure provides inhibitors of c-Jun N-terminal kinases (JNK) having a structure according to the following formula (I): or a salt or solvate thereof, wherein ring A, Ca, Cb, Z, R5, W and Cy are defined herein. The disclosure further provides pharmaceutical compositions including the compounds of the present disclosure and methods of making and using the compounds and compositions of the present disclosure, e.g., in the treatment and prevention of various disorders, such as Alzheimer's disease.