852068-22-5Relevant academic research and scientific papers
Development of a highly β-selective ribosylation reaction without using neighboring group participation: Total synthesis of (+)-caprazol, a core structure of caprazamycins
Hirano, Shinpei,Ichikawa, Satoshi,Matsuda, Akira
, p. 9936 - 9946 (2008/09/17)
(Chemical Equation Presented) Full details of the total synthesis of (+)-caprazol are described. The key elements of our approach include the early stage introduction of the aminoribose in a highly β-selective manner, using the steric hindrance in the tra
Synthesis of complex nucleoside antibiotics
Ichikawa, Satoshi,Matsuda
, p. 319 - 329 (2007/10/03)
Herbicidin B and fully protected tunicaminyluracil, which were undecose nucleoside antibiotics, were synthesized using a samarium diiodide (SmI 2) mediated aldol reaction with the use of α-phenylthioketone as an enolate. The characteristics of
Total synthesis of caprazol, a core structure of the caprazamycin antituberculosis antibiotics
Hirano, Shinpei,Ichikawa, Satoshi,Matsuda, Akira
, p. 1854 - 1856 (2007/10/03)
TB and anti-TB: Two key steps in the synthesis of caprazol (1), a core structure of the antituberculosis antibiotics, are the introduction of an aminoribose moiety by β-selective ribosylation without the use of neighboring-group participation and the construction of the diazepanone moiety. (Chemical Equation Presented)
