852106-25-3

Basic information

• Product Name: 2-(3,5-bis-(trifluoromethyl)phenyl)furan
• Synonyms: 2-(3,5-bis-(trifluoromethyl)phenyl)furan
• CAS NO: 852106-25-3
• Molecular Weight: 280.169
• Mol File: 852106-25-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 2-(3,5-bis-(trifluoromethyl)phenyl)furan(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,5-bis-(trifluoromethyl)phenyl)furan(852106-25-3)
• EPA Substance Registry System: 2-(3,5-bis-(trifluoromethyl)phenyl)furan(852106-25-3)

Safety Data

• Hazardous Substances Data: 852106-25-3(Hazardous Substances Data)

Upstream product

• 328-74-5 3,5-Bis-(trifluoromethyl)aniline 
• 110-00-9 furan 
• 328-70-1 3,6-bis(trifluoromethyl)bromobenzene 

Downstream Products

• 852106-50-4 8-(3,5-bis-(trifluoromethyl)phenyl)-2-fluoro-1,4,5-trimethoxynaphthalene 
• 852106-32-2 4-(3,5-bis-(trifluoromethyl)phenyl)-6-fluoro-5,8-dimethoxy-1-naphthol 

Relevant articles and documents

Electrochemical Synthesis of Biaryls via Oxidative Intramolecular Coupling of Tetra(hetero)arylborates

We report herein versatile, transition metal-free and additive-free (hetero)aryl-aryl coupling reactions promoted by the oxidative electrocoupling of unsymmetrical tetra(hetero)arylborates (TABs) prepared from ligand-exchange reactions on potassium trifluoroarylborates. Exploiting the power of electrochemical oxidations, this method complements the existing organoboron toolbox. We demonstrate the broad scope, scalability, and robustness of this unconventional catalyst-free transformation, leading to functionalized biaryls and ultimately furnishing drug-like small molecules, as well as late stage derivatization of natural compounds. In addition, the observed selectivity of the oxidative coupling reaction is related to the electronic structure of the TABs through quantum-chemical calculations and experimental investigations.

1,4-Difluoro-2,5-dimethoxybenzene as a precursor for iterative double benzyne-furan Diels-Alder reactions

(Chemical Equation Presented) The use of 1,4-difluoro-2,5-dimethoxybenzene as a novel precursor for iterative two-directional benzyne-furan Diels-Alder reactions, using a range of 2- and 3-substituted furans, is reported. Substituted oxabenzonorbornadiene