85217-80-7Relevant academic research and scientific papers
Preparation of some Allylic Sulphones; Base-catalysed Isomerisation and Deuteriation of Cyclohex-2-enyl p-Tolyl Sulphones
Knight, Derek J.,Lin, Peter,Russell, Simon T.,Whitham, Gordon H.
, p. 2701 - 2706 (2007/10/02)
A summary of the methods used in the preparation of a range of allylic sulphones is given.In the case of the conformationally biased sulphones (5) and (6) stereospecific preparation from the cis- and trans-5-t-butylcyclohex-2-en-1-ols was achieved by rear
PALLADIUM-CATALYZED REACTION OF ALLYL CARBAMATES; ALLYLATION OF CARBONUCLEOPHILES, AND PROTECTION-DEPROTECTION OF AMINES
Minami, Ichiro,Ohashi, Yukihiro,Shimizu, Isao,Tsuji, Jiro
, p. 2449 - 2452 (2007/10/02)
Allylation of carbonucleophiles with allylic carbamates under neutral conditions has been studied.The C-allylation of carbonucleophile is competitive with the N-allylation of amines, and the structure of amines is crucial for the selectivity.Bulky secondary amines gave the best results.Also a new method of protection-deprotection of amines as carbamates has been developed.Smooth deprotection is possible by the palladium-catalyzed reaction of allyl carbamates with formic acid.This method is particulary useful for primary amines, including optically active amino acids.
Allylic Carbonates. Efficient Allylating Agents of Carbonucleophiles in Palladium-Catalyzed Reactions under Neutral Conditions
Tsuji, Jiro,Shimizu, Isao,Minami, Ichiro,Ohashi, Yukihiro,Sugiura, Teruo,Takahashi, Kazuhiko
, p. 1523 - 1529 (2007/10/02)
Allylation of β-keto esters or malonates was carried out in good yields under neutral conditions by using allylic carbonates in the presence of palladium-phospine catalyst.Although simple ketones, esters, nitriles, and sulfones hardly react with allylic carbonates, α-alkenyl or α-aryl ketones, esters, nitriles, and sulfones were also allylated by using palladium-bis(diphenylphosphino)ethane catalyst under neutral conditions.
FACILE PALLADIUM CATALYZED DECARBOXYLATIVE ALLYLATION OF ACTIVE METHYLENE COMPOUNDS UNDER NEUTRAL CONDITIONS USING ALLYLIC CARBONATES
Tsuji, Jiro,Shimizu, Isao,Minami, Ichiro,Ohashi, Yukihiro
, p. 4809 - 4812 (2007/10/02)
Palladium catalyzed decarboxylative allylation of active methylene compounds proceeded under mild neutral conditions using allylic carbonates, which are much more reactive than allylic acetates or phenoxides used commonly in the reaction.
