852202-45-0Relevant articles and documents
Access to optically pure nitrogen heterocycles based on hydrozirconation of unsaturated secondary amines
Ahari, M'hamed,Joosten, Antoine,Vasse, Jean-Luc,Szymoniak, Jan
, p. 61 - 68 (2008/12/21)
Optically active N-heterocycles with four-, five-, or six-membered rings can be prepared from unsaturated secondary amines, by using a one-pot hydrozirconation/iodination sequence as the key step. The presented method allows the preparation of 2-substituted pyrrolidines enantiomeric to those previously obtained from N-allyloxazolidines. The two approaches use the same reagents (allyl bromide and aldehydes) and the same (R)-2-phenyl-glycinol as the chiral inductor. Georg Thieme Verlag Stuttgart.
Indium-mediated asymmetric barbier-type allylation of aldimines in alcoholic solvents: Synthesis of optically active homoallylic amines
Vilaivan, Tirayut,Winotapan, Chutima,Banphavichit, Vorawit,Shinada, Tetsuro,Ohfune, Yasufumi
, p. 3464 - 3471 (2007/10/03)
(Chemical Equation Presented) Chiral aldimines derived from phenylglycinol were diastereoselectively allylated with indium powder/allyl bromide in alcoholic solvents. Both aliphatic and aromatic aldimines provided good yield of the desired products with h