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(1R,2R)-N-(2,4,6-TRIMETHYLPHENYLSULFONYL)-1,2-DIPHENYLETHANE-1,2-DIAMINE, also known as TMDPD, is a chiral diamine compound that serves as a ligand in transition metal-catalyzed asymmetric synthesis. Its structure features a bulky substituent on the nitrogen atom, which creates steric hindrance and aids in controlling the enantioselectivity of catalytic reactions. TMDPD is recognized for its unique structure and chiral properties, making it a valuable asset in organic synthesis, especially in the production of pharmaceuticals and fine chemicals.

852212-90-9

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852212-90-9 Usage

Uses

Used in Pharmaceutical Industry:
TMDPD is utilized as a chiral ligand for the synthesis of enantioselective pharmaceuticals, contributing to the production of drugs with specific biological activity and reduced side effects. Its ability to control the enantioselectivity of catalytic reactions ensures the creation of the desired enantiomer, which is crucial for the efficacy and safety of many medications.
Used in Fine Chemicals Industry:
In the fine chemicals industry, TMDPD is employed as a ligand in asymmetric synthesis to produce enantiomerically pure compounds. These compounds are essential in the fragrance, flavor, and agrochemical sectors, where the purity and specific stereochemistry of the molecules are critical for their performance and safety.
Used in Asymmetric Hydrogenation:
TMDPD is used as a ligand in asymmetric hydrogenation reactions, a key technique in organic synthesis. This application allows for the selective reduction of prochiral compounds to their chiral counterparts, which is vital for the production of biologically active molecules and enantiomerically pure compounds.
Used in Asymmetric Allylic Substitution:
(1R,2R)-N-(2,4,6-TRIMETHYLPHENYLSULFONYL)-1,2-DIPHENYLETHANE-1,2-DIAMINE TMDPD is also used in asymmetric allylic substitution, another important class of reactions in organic chemistry. This process enables the selective substitution of allyl compounds, leading to the formation of new chiral centers and the synthesis of complex molecules with specific stereochemistry.
Used in Asymmetric Addition Reactions:
TMDPD functions as a ligand in asymmetric addition reactions, facilitating the enantioselective addition of nucleophiles to various substrates. This capability is crucial for the construction of chiral centers in organic molecules, which is essential for the development of new pharmaceuticals and other specialty chemicals.

Check Digit Verification of cas no

The CAS Registry Mumber 852212-90-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,2,2,1 and 2 respectively; the second part has 2 digits, 9 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 852212-90:
(8*8)+(7*5)+(6*2)+(5*2)+(4*1)+(3*2)+(2*9)+(1*0)=149
149 % 10 = 9
So 852212-90-9 is a valid CAS Registry Number.

852212-90-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name N-[(1R,2R)-2-amino-1,2-diphenylethyl]-2,4,6-trimethylbenzenesulfonamide

1.2 Other means of identification

Product number -
Other names (1R,2R)-N-(2,4,6-trimethylphenylsulfonyl)-1,2-diphenylethane-1,2-diamine

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:852212-90-9 SDS

852212-90-9Upstream product

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