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Phosphonic acid, [3-[4-(1,1-dimethylethyl)-2,5-dihydroxyphenyl]-3-methylbutyl]-, dimethyl ester, commonly known as zoledronic acid, is a potent bisphosphonate drug that plays a significant role in maintaining bone health and preventing skeletal complications in various medical conditions. It is characterized by its ability to inhibit bone breakdown and increase bone density, making it an effective treatment for osteoporosis and other bone-related disorders.

85224-97-1

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85224-97-1 Usage

Uses

Used in Orthopedic Applications:
Zoledronic acid is used as a bone-preserving agent for the prevention and treatment of osteoporosis. It works by inhibiting the breakdown of bone, leading to increased bone density and reduced risk of fractures.
Used in Oncology Applications:
In cancer patients, zoledronic acid is used to prevent bone complications such as fractures and spinal cord compression. It helps to maintain bone integrity and reduce the risk of skeletal-related events in patients with bone metastases.
Used in the Treatment of Paget's Disease of Bone:
Zoledronic acid is approved for the treatment of Paget's disease of bone, a condition characterized by abnormal bone metabolism and excessive bone resorption. It helps to normalize bone turnover and alleviate symptoms associated with the disease.
Used in the Management of Hypercalcemia of Malignancy:
Zoledronic acid is effective in managing hypercalcemia of malignancy, a condition where high levels of calcium in the blood are caused by cancer. It helps to lower calcium levels and alleviate related symptoms.
Used in Pharmaceutical Formulations:
The dimethyl ester form of zoledronic acid allows for improved bioavailability and better absorption in the body. This enhances the drug's efficacy and makes it more suitable for various pharmaceutical formulations and applications.

Check Digit Verification of cas no

The CAS Registry Mumber 85224-97-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,2,2 and 4 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 85224-97:
(7*8)+(6*5)+(5*2)+(4*2)+(3*4)+(2*9)+(1*7)=141
141 % 10 = 1
So 85224-97-1 is a valid CAS Registry Number.

85224-97-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name dimethyl 3-(4'-t-butyl-2',5'-dihydroxyphenyl)-3-methyl-butane-phosphonate

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:85224-97-1 SDS

85224-97-1Upstream product

85224-97-1Downstream Products

85224-97-1Relevant academic research and scientific papers

Hydroquinones

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, (2008/06/13)

New hydroquinones have the formula: STR1 wherein p is 1 or 2 and q is 0 or 1, provided that p+q is 1 or 2; R is a residue of formula: STR2 wherein Q is (i) -OX or (ii) -PO(OR11)((O)x R11); and salts thereof with organic or inorganic acid bases. The groups X and R11 and x are defined hereinafter. The compounds of formula I are useful as stabilisers in photographic materials.

Hydroquinones

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, (2008/06/13)

New hydroquinones having the formula: STR1 wherein p is 1 or 2 and q is 0 or 1, provided that p+q is 1 or 2; R is a residue of formula: STR2 wherein Q is selected from the residues --COZR4 wherein Z is 0 or NR5, --OX wherein X is R5 or --COR7, --NR8 R9, --PO(OR10)[O]x R11 wherein x is 0 or 1, --SO2 R12 or --CN, and salts thereof with organic or inorganic acid bases. The groups, R1, R2, R3, R4, R5, R7, R8, R9, R10, R11, R12, k and n are defined hereafter. These compounds are used as stabilizers in photographic materials.

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