85235-01-4Relevant academic research and scientific papers
Regioselectivity in Organo-Transition-Metal Chemistry. A New Indicator Substrate for Classification of Nucleophiles
Keinan, Ehud,Roth, Zeev
, p. 1769 - 1772 (2007/10/02)
A new model for the characterization of nucleophiles is proposed, based on the regioselectivity of the reaction of a given nucleophile with 3-acetoxy-3-cyano-1-phenylpropene (14) in the presence of Pd(0) catalyst.A general correlation between regioselectivity using this indicator substrate and literature data on stereospecificity of nucleophilic substitution in other model compounds is apparent.
