852475-58-2Relevant academic research and scientific papers
Design, synthesis, and biological evaluation of 10-methanesulfonyl-DDACTHF, 10-methanesulfonyl-5-DACTHF, and 10-methylthio-DDACTHF as potent inhibitors of GAR Tfase and the de novo purine biosynthetic pathway
Cheng, Heng,Chong, Youhoon,Hwang, Inkyu,Tavassoli, Ali,Zhang, Yan,Wilson, Ian A.,Benkovic, Stephen J.,Boger, Dale L.
, p. 3577 - 3585 (2007/10/03)
The synthesis and evaluation of 10-methanesulfonyl-DDACTHF (1), 10-methanesulfonyl-5-DACTHF (2), and 10-methylthio-DDACTHF (3) as potential inhibitors of glycinamide ribonucleotide transformylase (GAR Tfase) and aminoimidazole carboxamide ribonucleotide t
