852534-79-3

Upstream product

• 4755-77-5 Ethyl oxalyl chloride 
• 263559-08-6 2-amino-N-(4-(trifluoromethyl)phenyl)benzamide 

Downstream Products

• 830324-84-0 4-oxo-3-(4-trifluoromethyl-phenyl)-3,4-dihydro-quinazoline-2-carboxylic acid benzylamide 
• 830324-91-9 4-oxo-3,4-dihydro-quinazoline-2-carboxylic acid benzyl-(4-trifluoromethyl-phenyl)-amide 
• 830324-85-1 4-oxo-3-(4-trifluoromethyl-phenyl)-3,4-dihydro-quinazoline-2-carboxylic acid butylamide 
• 830324-83-9 4-oxo-3-(4-trifluoromethyl-phenyl)-3,4-dihydro-quinazoline-2-carboxylic acid phenylamide 
• 53451-87-9 phenyl(4-trifluoromethylphenyl)amine 
• 405-81-2 N-benzyl-4-(trifluoromethyl)aniline 
• 852534-84-0 3,4-dihydro-4-oxo-3-[4-(trifluoromethyl)phenyl]-2-quinazolinecarbothioic acid S-p-tolyl ester 
• 361180-29-2 4-oxo-3-(4-trifluoromethyl-phenyl)-3,4-dihydro-quinazoline-2-carboxylic acid ethyl ester 

Relevant academic research and scientific papers

Synthetic studies on 3-arylquinazolin-4-ones: Intramolecular nucleophilic aromatic substitution reaction of 2-carboxamido-3-arylquinazolin-4-ones and its application to the synthesis of secondary aryl amines

The general synthesis and a novel intramolecular nucleophilic aromatic substitution (SNAr) reaction of 2-carboxamido-3-arylquinazolin-4- ones, a potentially useful scaffold in the field of medicinal chemistry, are described. The synthetic utili