852546-60-2

Upstream product

• 164414-39-5 acetic acid (1R,4S)-(-)-(tert-butyldimethylsiloxy)cyclohex-2-enyl ester 
• 164577-42-8 <(4R)-(+)-tert-Butoxydimethylsiloxy>-2-cyclohexen-1-on 
• 164414-40-8 cis-(1S,4R)-4-(tert-butyldimethylsilyloxy)cyclohex-2-enol 
• 852546-51-1 (Z)-methyl trans-4,5-(isopropylidenedioxy)-2-hexenoate 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 132617-05-1 acetic acid (1S,4R)-(-)-4-hydroxycyclohex-2-enyl ester 
• 99603-55-1 (4S,5R)-2,2,5-trimethyl-1,3-dioxolane-4-carbaldehyde 
• 852546-64-6 2,2-Dimethyl-propionic acid (1S,2R,3R,4S,5S,7R)-7-(tert-butyl-dimethyl-silanyloxy)-5-hydroxy-3-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-bicyclo[2.2.2]oct-2-ylmethyl ester 
• 852546-54-4 2,2-Dimethyl-propionic acid (1S,2R,3R,4S,7R)-7-(tert-butyl-dimethyl-silanyloxy)-5-oxo-3-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-bicyclo[2.2.2]oct-2-ylmethyl ester 
• 852546-53-3 (1S,2S,4S,5R,6R,8R)-8-(tert-Butyl-dimethyl-silanyloxy)-5-hydroxymethyl-6-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-bicyclo[2.2.2]octan-2-ol 
• 852546-52-2 (1S,2R,3S,4S,7R)-7-(tert-Butyl-dimethyl-silanyloxy)-5-oxo-3-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-bicyclo[2.2.2]octane-2-carboxylic acid methyl ester 
• 852546-68-0 (1S,4S,5R,6R,8R)-8-(tert-Butyl-dimethyl-silanyloxy)-5-hydroxymethyl-6-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-bicyclo[2.2.2]octan-2-one 
• 852546-59-9 (1S,4S,5R,6R,8R)-8-(tert-Butyl-dimethyl-silanyloxy)-5-(4-methoxy-benzyloxymethyl)-6-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-bicyclo[2.2.2]octan-2-one 
• 103731-34-6 (E)-1-(tri-n-butylstannyl)-2-(dimethylphenylsilyl)ethene 

Downstream Products

• 852546-70-4 Thiocarbonic acid O-[(1S,2R,4S,5S,7R,8R)-5-[(E)-2-(dimethyl-phenyl-silanyl)-vinyl]-5-hydroxy-7-(4-methoxy-benzyloxymethyl)-8-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-bicyclo[2.2.2]oct-2-yl] ester O-p-tolyl ester 
• 852546-57-7 (1S,2S,4R,7R,8R)-2-[(E)-2-(Dimethyl-phenyl-silanyl)-vinyl]-8-(4-methoxy-benzyloxymethyl)-7-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-bicyclo[2.2.2]oct-5-en-2-ol 
• 852546-71-5 (1R,2R)-1-[(1S,2R,3R,4R,7S)-7-[(E)-2-(Dimethyl-phenyl-silanyl)-vinyl]-7-hydroxy-3-(4-methoxy-benzyloxymethyl)-bicyclo[2.2.2]oct-5-en-2-yl]-propane-1,2-diol 
• 852546-69-1 (1S,2S,4S,5R,7R,8R)-2-[(E)-2-(Dimethyl-phenyl-silanyl)-vinyl]-8-(4-methoxy-benzyloxymethyl)-7-((4R,5R)-2,2,5-trimethyl-[1,3]dioxolan-4-yl)-bicyclo[2.2.2]octane-2,5-diol 

Relevant academic research and scientific papers

Synthetic studies toward the construction of the cis-decalin portion of superstolides A and B. Application of a sequential double Michael reaction and an anionic oxy-Cope rearrangement

(Chemical Equation Presented) A highly convergent strategy for the asymmetric synthesis of the cis-decalin portion of the antitumor macrolide superstolide A was developed. The key reactions in our approach involve a sequential double Michael reaction and