852570-80-0

Basic information

• Product Name: 5-BROMOISOQUINOLIN-1-AMINE
• Synonyms: 5-BROMOISOQUINOLIN-1-AMINE;1-Amino-5-bromoisoquinoline;5-Bromo-1-isoquinolinamine;5-Bromoisoquinolin-1-amine, 1-Amino-5-bromo-2-azanaphthalene;5-bromoisoquinolin-1-ylamine
• CAS NO: 852570-80-0
• Molecular Formula: C₉H₇BrN₂
• Molecular Weight: 223.07
• Product Categories: Building Blocks;Isoquinoline
• Mol File: 852570-80-0.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 380.7 °C at 760 mmHg
• Flash Point: 184 °C
• Appearance: /
• Density: 1.649
• Vapor Pressure: 5.35E-06mmHg at 25°C
• Refractive Index: 1.732
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• PKA: 6.50±0.43(Predicted)
• CAS DataBase Reference: 5-BROMOISOQUINOLIN-1-AMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-BROMOISOQUINOLIN-1-AMINE(852570-80-0)
• EPA Substance Registry System: 5-BROMOISOQUINOLIN-1-AMINE(852570-80-0)

Safety Data

• Statements: 41
• Safety Statements: 26-39
• Hazardous Substances Data: 852570-80-0(Hazardous Substances Data)

Usage

General Description

5-Bromoisoquinolin-1-amine is a chemical compound with the molecular formula C9H7BrN2. It is a derivative of isoquinoline and contains a bromine atom. 5-Bromoisoquinolin-1-amine has been studied for its potential applications in medicinal chemistry, particularly for its potential use as a building block in the synthesis of various bioactive molecules. It has been investigated for its potential as a pharmaceutical intermediate and for its ability to interact with biological targets. 5-Bromoisoquinolin-1-amine is an important chemical that is of interest to researchers in the fields of organic chemistry and drug discovery.

InChI:InChI=1/C9H7BrN2/c10-8-3-1-2-7-6(8)4-5-12-9(7)11/h1-5H,(H2,11,12)

Upstream product

• 34551-41-2 5-bromo-1-chloroisoquinoline 

Downstream Products

• 1481641-08-0 C₂₃H₂₃N₅O₂ 

Relevant articles and documents

BRIDGED BICYCLIC KALLIKREIN INHIBITORS

Provided herein are kallikrein modulating compounds, pharmaceutical compositions comprising the same, and uses thereof.

SUBSTITUTE ISOQUINOLINES USEFUL IN THE TREATMENT OF DISEASES SUCH AS CANCER AND ATHEROSCLEROSIS

A compound of Formula (I) wherein: One of R1 and R2 is H and the other represents - NHCONHR4 wherein R4 represents a phenyl or naphthyl group (which may be optionally substituted by one or more substituents independently selected from -C1-6 alkyl, -C1-6 haloalkyl, - CH2CH2CH2-, halogen, C1-6 alkoxy, C1-6 haloalkoxy, OH, NO2), C3-7 cycloalkyl or R4 together with the NH to which it is bonded forms a morpholino group and R3 is H or NHR5 wherein R5 is H, -quinolinyl or -isoquinolinyl, -(CONH)p phenyl (wherein p is 0 or 1 and the phenyl is optionally substituted by one or more substituents independently selected from halogen, -C1-6 alkyl, -C1-6 haloalkyl, -morpholino, -SO2NH2, benzothiazole (substituted by methyl)) or a salt, solvate, or physiologically functional derivative thereof.