852619-55-7

Basic information

• Product Name: N-phenyl-N'-(2-tritylsulfanyl-ethyl)-succinamide
• CAS NO: 852619-55-7
• Molecular Weight: 494.657
• Mol File: 852619-55-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-phenyl-N'-(2-tritylsulfanyl-ethyl)-succinamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-phenyl-N'-(2-tritylsulfanyl-ethyl)-succinamide(852619-55-7)
• EPA Substance Registry System: N-phenyl-N'-(2-tritylsulfanyl-ethyl)-succinamide(852619-55-7)

Safety Data

• Hazardous Substances Data: 852619-55-7(Hazardous Substances Data)

Upstream product

• 62-53-3 aniline 
• 1095-85-8 2-amino tritylthio ethane 
• 102-14-7 N-phenyl-succinamic acid 
• 5430-83-1 N-phenyl-succinamic acid methyl ester 

Relevant articles and documents

Mercaptoamide-based non-hydroxamic acid type histone deacetylase inhibitors

Inhibitors of histone deacetylases (HDAC) are emerging as a promising class of anti-cancer agents. A mercaptoamide functionality was designed as a bidentate zinc chelator and incorporated into the hydroxamic acid based SAHA (1) scaffold in order to identify non-hydroxamate compounds as potential inhibitors of histone deacetylases. Two sets of mercaptoamides 2 and 3 with varying spacer length were synthesized and their HDAC inhibitory activity was evaluated. Low micromolar inhibition was observed for mercaptoamides 2e, 3b, and 3d.