852657-49-9Relevant academic research and scientific papers
Ethyl (benzothiazol-2-ylsulfonyl)acetate: A new reagent for the stereoselective synthesis of α,β-unsaturated esters from aldehydes
Blakemore, Paul R.,Ho, Danny K.H.,Nap, W. Mieke
, p. 1365 - 1368 (2005)
The title reagent engaged in the modified Julia olefination with aldehydes under mild reaction conditions (DBU, CH2Cl2, rt or -78°C) to yield α,β-unsaturated esters; aryl aldehydes and aliphatic aldehydes possessing significant chain branching elements gave trans alkene products with high stereoselectivity (E : Z up to >98 : 2), while straight chain aliphatic aldehydes gave cis products preferentially (Z : E up to 92 : 8). The Royal Society of Chemistry 2095.
