85274-81-3 Usage
Uses
Used in Pharmaceutical Industry:
2-chloro-3-(4-chlorophenyl)quinoline is used as a potential therapeutic agent for its medicinal properties, given the known therapeutic nature of quinoline compounds. Its unique structure may offer new avenues for drug development and treatment of various diseases.
Used in Chemical Research:
2-chloro-3-(4-chlorophenyl)quinoline is used as a research compound for studying its reactivity, synthesis methods, and potential interactions with other chemicals. Understanding its properties can contribute to the advancement of chemical sciences and the discovery of new applications.
Used in Material Science:
2-chloro-3-(4-chlorophenyl)quinoline is used as a component in the development of new materials, potentially for applications in various industries. Its unique structure may provide properties that are beneficial in the creation of novel materials with specific characteristics.
Safety Precautions:
Due to the presence of chlorine atoms, 2-chloro-3-(4-chlorophenyl)quinoline may require special handling and safety measures to prevent potential hazards. It is important to consider the toxicity and reactivity of 2-chloro-3-(4-chlorophenyl)quinoline when planning its use in any application.
Check Digit Verification of cas no
The CAS Registry Mumber 85274-81-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,2,7 and 4 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 85274-81:
(7*8)+(6*5)+(5*2)+(4*7)+(3*4)+(2*8)+(1*1)=153
153 % 10 = 3
So 85274-81-3 is a valid CAS Registry Number.
InChI:InChI=1/C15H9Cl2N/c16-12-7-5-10(6-8-12)13-9-11-3-1-2-4-14(11)18-15(13)17/h1-9H
85274-81-3Relevant academic research and scientific papers
Synthesis of 2-halogenated quinolines by halide-mediated intramolecular cyclization of o-alkynylaryl isocyanides
Mitamura, Takenori,Nomoto, Akihiro,Sonoda, Motohiro,Ogawa, Akiya
supporting information; experimental part, p. 822 - 824 (2010/09/06)
When o-alkynylaryl isocyanides 1 are treated with triethylamine in chloroform, intramolecular chlorinating cyclization of the isocyanides takes place, affording the corresponding 2-chlorinated quinoline derivatives 2 in good to excellent yields, selective
Tetrabutylammonium chloride-triggered 6-endo cyclization of o-alkynylisocyanobenzenes: an efficient synthesis of 2-chloro-3-substituted quinolines
Liu, Lanying,Wang, Yong,Wang, Honggen,Peng, Changlan,Zhao, Jiaji,Zhu, Qiang
experimental part, p. 6715 - 6719 (2010/01/18)
A highly efficient one-pot synthesis of 2-chloro-3-substituted quinolines has been developed by tetrabutylammonium chloride-triggered 6-endo cyclization of o-alkynylisocyanobenzenes, which are generated in situ by dehydration of the corresponding N-(2-eth
Synthesis and 5-Hydroxytryptamine Antagonist Activity of 2-thio>-3-phenylquinoline and Its Analogues
Blackburn, Thomas P.,Cox, Barry,Guildford, Allen J.,Count, David J. Le,Middlemiss, Derek N.,et al.
, p. 2252 - 2259 (2007/10/02)
A series of 2-quinolines substituted at the 3-position with alkyl, aryl, or heteroaryl groups has been prepared in the search for novel and selective 5-HT2 antagonists.The affinity of the compounds for 5-HT1 recep
