85274-82-4 Usage
Uses
Used in Pharmaceutical Industry:
3-(4-BROMOPHENYL)-2-CHLOROQUINOLINE is used as a bioactive compound for its potential role in drug discovery and development. Its unique structure and reactivity contribute to the design and synthesis of new therapeutic agents.
Used in Medicinal Chemistry Research:
3-(4-BROMOPHENYL)-2-CHLOROQUINOLINE is employed as a key intermediate in the synthesis of various pharmaceutical compounds. Its bromophenyl and chlorine substituents allow for further functionalization and modification, enabling the exploration of novel drug candidates with improved properties and therapeutic effects.
Used in Chemical Reactions:
3-(4-BROMOPHENYL)-2-CHLOROQUINOLINE is utilized as a reactive intermediate in various chemical processes. Its bromine and chlorine atoms facilitate substitution and other reactions, making it a valuable building block for the synthesis of complex organic molecules and advanced materials.
Check Digit Verification of cas no
The CAS Registry Mumber 85274-82-4 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,5,2,7 and 4 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 85274-82:
(7*8)+(6*5)+(5*2)+(4*7)+(3*4)+(2*8)+(1*2)=154
154 % 10 = 4
So 85274-82-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H9BrClN/c16-12-7-5-10(6-8-12)13-9-11-3-1-2-4-14(11)18-15(13)17/h1-9H
85274-82-4Relevant academic research and scientific papers
Tetrabutylammonium chloride-triggered 6-endo cyclization of o-alkynylisocyanobenzenes: an efficient synthesis of 2-chloro-3-substituted quinolines
Liu, Lanying,Wang, Yong,Wang, Honggen,Peng, Changlan,Zhao, Jiaji,Zhu, Qiang
experimental part, p. 6715 - 6719 (2010/01/18)
A highly efficient one-pot synthesis of 2-chloro-3-substituted quinolines has been developed by tetrabutylammonium chloride-triggered 6-endo cyclization of o-alkynylisocyanobenzenes, which are generated in situ by dehydration of the corresponding N-(2-eth
Synthesis and 5-Hydroxytryptamine Antagonist Activity of 2-thio>-3-phenylquinoline and Its Analogues
Blackburn, Thomas P.,Cox, Barry,Guildford, Allen J.,Count, David J. Le,Middlemiss, Derek N.,et al.
, p. 2252 - 2259 (2007/10/02)
A series of 2-quinolines substituted at the 3-position with alkyl, aryl, or heteroaryl groups has been prepared in the search for novel and selective 5-HT2 antagonists.The affinity of the compounds for 5-HT1 recep
