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(R)-4-(4-((2-(4-chlorophenyl)-5,5-dimethylcyclohex-1-enyl)methyl)piperazin-1-yl)-N-(4-(4-(dimethylamino)-1-(phenylthio)butan-2-ylamino)-3-nitrophenylsulfonyl)benzamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

852811-25-7

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852811-25-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 852811-25-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,5,2,8,1 and 1 respectively; the second part has 2 digits, 2 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 852811-25:
(8*8)+(7*5)+(6*2)+(5*8)+(4*1)+(3*1)+(2*2)+(1*5)=167
167 % 10 = 7
So 852811-25-7 is a valid CAS Registry Number.

852811-25-7Downstream Products

852811-25-7Relevant academic research and scientific papers

Discovery of an orally bioavailable small molecule inhibitor of prosurvival B-cell lymphoma 2 proteins

Park, Cheol-Min,Bruncko, Milan,Adickes, Jessica,Bauch, Joy,Ding, Hong,Kunzer, Aaron,Marsh, Kennan C.,Nimmer, Paul,Shoemaker, Alexander R.,Song, Xiaohong,Tahir, Stephen K.,Tse, Christin,Wang, Xilu,Wendt, Michael D.,Yang, Xiufen,Zhang, Haichao,Fesik, Stephen W.,Rosenberg, Saul H.,Elmore, Steven W.

experimental part, p. 6902 - 6915 (2009/11/30)

Overexpression of prosurvival proteins such as Bcl-2 and Bcl-XL has been correlated with tumorigenesis and resistance to chemotherapy, and thus, the development of antagonists of these proteins may provide a novel means for the treatment of can

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