852852-86-9Relevant academic research and scientific papers
N-methyl-N-nosyl-β3-amino acids
Belsito, Emilia,Di Gioia, Maria L.,Greco, Antonella,Leggio, Antonella,Liguori, Angelo,Perri, Francesca,Siciliano, Carlo,Viscomi, Maria C.
, p. 4798 - 4802 (2008/02/05)
(Chemical Equation Presented) N-Methyl-β3-amino acids are important building blocks in the synthesis of biologically active molecules. A very simple and efficient approach to transform natural α-amino acids into their corresponding N-methyl-βs
N-methylation of peptides on selected positions during the elongation of the peptide chain in solution phase
Di Gioia, M. Luisa,Leggio, Antonella,Liguori, Angelo
, p. 3892 - 3897 (2007/10/03)
An efficient and general solution-phase method for the site-specific N-methylation of peptides has been developed. This novel procedure involves synthesis of N-nosyl protected peptides and their subsequent N-methylation with diazomethane. Its efficiency w
