852867-30-2Relevant academic research and scientific papers
Reduction of indolo[2,3-b]quinoxalines
Engqvist, Robert,Stensland, Birgitta,Bergman, Jan
, p. 4495 - 4500 (2005)
Reduction of indolo[2,3-b]quinoxalines with zinc in the presence of an anhydride gave N,N-diacyl trapped 6,11-dihydroindolo[2,3-b]quinoxalines in 43-92% yields. When the reduction with zinc was performed in TFA/TFAA, an unexpected ring opened product was isolated in 49% yield. The structure of this product could be identified as 1,2-dihydro-1-trifluoroacetyl-3-[(2- trifluoroacetylamino)phenyl]quinoxaline.
Application of the Pictet-Spengler reaction to aryl amine substrates linked to deactivated aromatic heterosystems
Saha,Sharma,Sawant,Kundu
, p. 8676 - 8684 (2008/12/21)
Three new substrates with an aryl amine moiety attached to quinoxalines, triazoles and tetrazoles either via C or N have been used for the Pictet-Spengler reaction. The substrates have been designed by applying the concept of 'aryl amine attached to a dea
