852913-19-0

Basic information

• Product Name: Thiourea, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(8α,9S)-10,11-dihydro-6'-Methoxycinchonan-9-yl]-
• Synonyms: Thiourea, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(8α,9S)-10,11-dihydro-6'-Methoxycinchonan-9-yl]-;N-[3,5-Bis(trifluoromethyl)phenyl]-N′-[(8a,9S)-10,11-dihydro-6′-methoxy-9-cinchonanyl]thiourea ;N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(8a,9S)-10,11-dihydro-6'-methoxy-9-cinchonanyl]thiourea 90%;N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(8α,9S)-10,11-dihydro-6'-methoxycinchonan-9-yl]thiourea;N-[3,5-Bis(trifluoromethyl)phenyl]-N'-[(8α,9S)-10,11- dihydro-6'-methoxycinchonan-9-yl]thiourea,99%d.e.
• CAS NO: 852913-19-0
• Molecular Formula: C29H30F6N4OS
• Molecular Weight: 596.6301192
• Mol File: 852913-19-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 600.8±65.0 °C(Predicted)
• Appearance: /
• Density: 1.38±0.1 g/cm3(Predicted)
• PKA: 11.39±0.70(Predicted)
• CAS DataBase Reference: Thiourea, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(8α,9S)-10,11-dihydro-6'-Methoxycinchonan-9-yl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Thiourea, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(8α,9S)-10,11-dihydro-6'-Methoxycinchonan-9-yl]-(852913-19-0)
• EPA Substance Registry System: Thiourea, N-[3,5-bis(trifluoroMethyl)phenyl]-N'-[(8α,9S)-10,11-dihydro-6'-Methoxycinchonan-9-yl]-(852913-19-0)

Safety Data

• Hazard Codes: T
• Statements: 25
• Safety Statements: 45
• RIDADR: UN 2811 6.1 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 852913-19-0(Hazardous Substances Data)

Usage

General Description

Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-[(8α,9S)-10,11-dihydro-6'-methoxycinchonan-9-yl]- is a complex chemical compound that consists of a thiourea functional group and a cinchonan alkaloid moiety. It is commonly used as a chiral ligand in asymmetric catalysis for the synthesis of pharmaceuticals, agrochemicals, and other fine chemicals. The compound's unique structure provides it with the ability to facilitate various chemical reactions with high selectivity and efficiency. Additionally, its fluorous nature makes it easy to be separated and reused, which enhances its practicality in industrial applications. This chemical has shown promise in the field of organic synthesis and is a subject of ongoing research for its potential utility in the development of new chemical processes.

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Relevant articles and documents

Plant Process for the Preparation of Cinchona Alkaloid-Based Thiourea Catalysts

Cinchona alkaloid-based thiourea catalysts (1a and 1b) belong to an important class of bifunctional organocatalysts, which has been widely used for a variety of asymmetric reactions. The commercial availability of these catalysts is sporadic, and limited

Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts

(Chemical Equation Presented) Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.