852919-40-5Relevant academic research and scientific papers
Preparation of (Z)-1-fluoro-1-alkenyl carboxylates, carbonates and carbamates through chromium mediated transformation of dibromofluoromethylcarbinyl esters and the reactivity as double acyl group donors
Saito, Akio,Tojo, Manabu,Yanai, Hikaru,Wada, Fukiko,Nakagawa, Muga,Okada, Midori,Sato, Azusa,Okatani, Rieko,Taguchi, Takeo
experimental part, p. 38 - 51 (2012/02/04)
CrCl2/Mn-mediated transformation of various dibromofluoromethylcarbinyl esters including carboxylates, carbonates and carbamates provided 1-fluoro-1-alkenyl esters via [2,3]-sigmatropic rearrangement of ester group. Reaction proceeded by using CrCl2/Mn system under mild conditions (in THF at room temperature) to give 1-fluoro-1-alkenyl esters in good yield with an excellent Z selective manner. 1-Fluoro-1-alkenyl ester thus obtained acts as a double acyl donor in the reaction with necleophiles such as amine, thiol, alcohol as well as bifunctional necleophiles such as ethylene diamine derivative.
Stereoselective transformations of trihalomethylcarbinols induced by chromous chloride
Bejot, Romain,Tisserand, Steve,Ready, L. Manmohan,Barma, Deb K.,Baati, Rachid,Falck,Mioskowski, Charles
, p. 2008 - 2011 (2007/10/03)
(Chemical Equation Presented) Reduction of trihalomethylcarbinols 1 with CrCl2 affords good to excellent yields of (Z)-α-haloenol esters 2 and (Z)-β-haloenol ethers 3 through acyl or hydrogen migration, respectively. The reaction is proposed to
